Two novel mutations of the IRX4 gene in patients with congenital heart disease

Congenital Heart Disease Caused by Mutations in the Transcription Factor <i>NKX2-5</i>

Jean‐Jacques Schott, D. Woodrow Benson, Craig T. Basson et al. · Science · 1998 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +17

GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5

Vidu Garg, Irfan S. Kathiriya, R. Bowling Barnes et al. · Nature · 2003 · 1.2K citations

Medicine, Genetics, Molecular Genetics +14

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

Newbury-Ecob Ra, David I. Wilson, Andrew R.J. Curtis et al. · Nature Genetics · 1997 · 929 citations

Life Sciences, Genetics, Molecular Genetics +8

An analysis of the syndrome of malformations induced by maternal vitamin a deficiency. Effects of restoration of vitamin a at various times during gestation

James Wilson, Carolyn B. Roth, Josef Warkany · American Journal of Anatomy · 1953 · 756 citations

Public Health, Maternal Health, Obstetrics +13

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

Henry M. Sucov, E. D. Dyson, C L Gumeringer et al. · Genes & Development · 1994 · 632 citations · Full text

Life Sciences, Developmental Biology, Genetics +17