Concepedia
BMJ · 1991 · 140 citations · 10 references
Open access
Public HealthInternal MedicineClinical MedicineEvidence-based PracticeExperimental DesignClinical Trial DesignClinical TrialsRandomized Comparative TrialsRandomized Controlled TrialsStudy DesignPilot Randomized Controlled TrialsRandomized Clinical Trials
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MEDICAL SCIENCE GISSI-2: A factorial randomised trial of alteplase versus streptokinase and heparin versus no heparin among 12 490 patients with acute myocardial infarction
GRUPPOITALIANOPERLOSTUDIODELL · The Lancet · 1990 · 911 citations
Medicine, Cardiology, Internal Medicine +14
Why do we need some large, simple randomized trials?
Salim Yusuf, Rory Collins, Richard Peto · Statistics in Medicine · 1984 · 714 citations
Public Health, Biostatistics, Experimental Design +8
The State of the Art Versus the State of the Science: The Diffusion of New Medical Technologies into Practice
Ann Greer · International Journal of Technology Assessment in Health Care · 1988 · 351 citations
Social Sciences, Community Medicine, Communities Of Practice +12
Rationale and design of a randomized clinical trial on prevention of stroke in isolated systolic hypertension
Journal of Clinical Epidemiology · 1988 · 110 citations
Medicine, Cardiology, Preventive Medicine +13
The Impact of Patient Management Guidelines on the Care of Breast, Colorectal, and Ovarian Cancer Patients in Italy
Roberto Grilli, Giovanni Apolone, Silvia Marsoni et al. · Medical Care · 1991 · 66 citations
Medicine, Medical Education, Oncology +12