Carbazole alkaloids from the stems of <i>Clausena excavata</i>

Abstract

A new carbazole alkaloid, sansoakamine (8), together with 11 known compounds, was isolated from the stems of Clausena excavata. All structures were elucidated by spectroscopic methods. Compound 7 showed moderate anti-malarial activity against Plasmodium falciparum with a MIC value of 6.74 microg/ml.