Therapeutic Advances in Endocrinology and Metabolism · 2012 · 15 citations · 9 references
MedicineOrthopaedic SurgerySurgeryCell TherapyDiabetologyFoot SurgeryDiabetic Foot DiseaseDiabetic Foot Ulcer CareDiabetic Foot UlcerationFoot UlcerationFoot UlcersUlcer ManagementAdjunctive Platelet-rich Plasma TherapyAdvanced Wound TherapiesDiabetic Foot Ulcer SurgeryLower Extremity Amputation PreventionLower-limb AmputationNeuropathic Ulcer ManagementPlatelet-rich Plasma Injection
Nonhealing diabetic foot ulcers are a major complication in patients with diabetes. In an unacceptably high number of cases, the final treatment result is lower extremity amputation, which might have been avoided if an aggressive therapy had been carried out earlier. Emerging cellular therapies such as platelet-rich plasma gel provide completely new ulcer management options that might help to avoid limb loss [Driver, 2006].
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Antimicrobial Peptides from Human Platelets
Yi‐Quan Tang, Michael R. Yeaman, Michael E. Selsted · Infection and Immunity · 2002 · 570 citations