Texture-Based Quantification of Pulmonary Emphysema on High-Resolution Computed Tomography: Comparison With Density-Based Quantification and Correlation With Pulmonary Function Test

Abstract

Texture-based quantification of emphysema using an automated system showed better correlation with the PFT results than density-based quantification. Separate quantification of the BO, ME, and SE areas showed a different contribution of each component to the FEV(1)/FVC and the DLco. The proposed system can be successfully used for detailed regional and global evaluation of lung lesions on HRCT scanning for emphysema.