Digestion · 2009 · 65 citations · 0 references
MedicineOncologySurgeryMetastasisNeoplasiaSurgical OncologyEndocrine Tumor PathologyEndocrine Tumor SurgeryEndocrine TumorsNeuroendocrine Tumor SurgeryNeuroendocrine TumorsPancreatic CancerEndocrine Tumor ImmunohistochemistryEndocrine Tumor MetastasisLocal Tumor ResectionMetastatic Endocrine Tumor ResectionMetastatic Endocrine TumorsMetastatic Neuroendocrine TumorsPancreatic Neuroendocrine NeoplasmsParaganglioma Pathology
The present case report demonstrates the history of a 50-year-old man with a mixed endocrine-neurogenous tumor of the ampulla of Vater. The tumor was localized endoscopically after an attack of melena. There were no signs of endocrinopathy. A local resection with suturing of the pancreatic duct was performed. Morphologically, there were two different tissue types (neurogenous and carcinoid-like) with numerous cells and nerve fibers reacting immunohistochemically with somatostatin and neurotensin antisera: some immunoreactivity to PP-antibodies was observed. Still, after 20 months, the patient seems to have been cured by local resection.