Development and validation of an LC-MS-MS method for the determination of terfenadine in human plasma

Determination of terfenadine and terfenadine acid metabolite in plasma using solid-phase extraction and high-performance liquid chromatography with fluorescence detection

John E. Coutant, Patricia A. Westmark, Pasqua Nardella et al. · Journal of Chromatography B Biomedical Sciences and Applications · 1991 · 72 citations

Pharmacy, Pharmacology, Toxicology +15

In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Comparison to human liver microsomes and precision-cut liver tissue slices.

A. David Rodrigues, Darcy J. Mulford, R D Lee et al. · Drug Metabolism and Disposition · 1995 · 70 citations

Medicine, Biochemistry, Pharmacology +17

Bioavailability of terfenadine in man

Richard A. Okerholm, Daniel Weiner, R H Hook et al. · Biopharmaceutics & Drug Disposition · 1981 · 59 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +14

Radioimmunoassay for terfenadine in human plasma

C. E. Cook, David L. Williams, Mary Myers et al. · Journal of Pharmaceutical Sciences · 1980 · 25 citations

Medicine, Pharmacokinetics, Pharmacology +2

Determination of the metabolites of terfenadine in human urine by thermospray liquid chromatography—mass spectrometry

T.-M. Chen, Kenneth Y. Chan, John E. Coutant et al. · Journal of Pharmaceutical and Biomedical Analysis · 1991 · 23 citations

Pharmacy, Pharmacology, Toxicology +10