Concepedia

Synthesis of Chiral Chromium Tricarbonyl Labeled Thymine PNA Monomers via the Ugi Reaction

Clara Baldoli, Stefano Maiorana, Emanuela Licandro, Giovanna Zinzalla, Dario Perdicchia

Organic Letters · 2002 · 59 citations · 8 references

DOI

Concepts

Abstract

[reaction: see text] Ugi condensation was used to synthesize the first examples of chiral racemic Ar.Cr(CO)(3) labeled peptide nucleic acid (PNA) monomers bearing the organometallic moiety linked to the alpha-carbon of the glycine unit.

References

8

Multicomponent Reactions with Isocyanides

Alexander Dömlingꝉ, Ivar Ugi · Angewandte Chemie International Edition · 2000 · 4K citations

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Synthesis of Peptide Nucleic Acid Monomers Containing the Four Natural Nucleobases: Thymine, Cytosine, Adenine, and Guanine and Their Oligomerization

Kim L. Dueholm, Carsten Behrens, Leif Christensen et al. · The Journal of Organic Chemistry · 1994 · 303 citations

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Postcondensation Modifications of Ugi Four-Component Condensation Products:  1-Isocyanocyclohexene as a Convertible Isocyanide. Mechanism of Conversion, Synthesis of Diverse Structures, and Demonstration of Resin Capture

Thomas A. Keating, Robert W. Armstrong · Journal of the American Chemical Society · 1996 · 288 citations

, , +12

Resolution and asymmetric synthesis of ortho-substituted (benzaldehyde)tricarbonylchromium complexes

Alex Alexakis, Pierre Mangeney, Ilane Marek et al. · Journal of the American Chemical Society · 1992 · 105 citations

, , +6

A new application of bioorganometallics: the first simultaneous triple assay by the carbonylmetalloimmunoassay (CMIA) method

Michèle Salmain, Anne Vessières, Anne Varenne et al. · Journal of Organometallic Chemistry · 1999 · 46 citations

, , +9