Anti-tumor angiogenesis effect of aminopeptidase inhibitor bestatin against B16-BL6 melanoma cells orthotopically implanted into syngeneic mice

Definition of Two Angiogenic Pathways by Distinct α _v Integrins

Martin Friedlander, Peter C. Brooks, Robert W. Shaffer et al. · Science · 1995 · 1.3K citations

Life Sciences, Cell Biology, Molecular Biology +17

The role of angiogenesis in tumor growth.

J Folkman · PubMed · 1992 · 1.3K citations

Medicine, Cancer Biology, Oncology +12

Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis.

Renata Pasqualini, Erkki Koivunen, Renate Kain et al. · PubMed · 2000 · 867 citations

Medicine, Oncology, Pharmacology +16

Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis.

Michele Relf, S LeJeune, Prudence A. E. Scott et al. · PubMed · 1997 · 834 citations

Medicine, Cancer Biology, Oncology +12

Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N.

A. Thomas Look, RA Ashmun, Linda H. Shapiro et al. · Journal of Clinical Investigation · 1989 · 486 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12