Role and regulation of phospholipase D activity in normal and cancer cells

ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity

H. Alex Brown, Stephen Gutowski, Carolyn R. Moomaw et al. · Cell · 1993 · 905 citations

Life Sciences, Biochemistry, Molecular Biology +9

Stimulation of actin stress fibre formation mediated by activation of phospholipase D

Michael Cross, Sally Roberts, Anne J. Ridley et al. · Current Biology · 1996 · 211 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Analysis of the water-soluble products of phosphatidylcholine breakdown by ion-exchange chromatography. Bombesin and TPA (12-<i>O</i>-tetradecanoylphorbol 13-acetate) stimulate choline generation in Swiss 3T3 cells by a common mechanism

Simon J. Cook, Michael J.O. Wakelam · Biochemical Journal · 1989 · 189 citations · Full text

Life Sciences, Biochemistry, Cell Biology +13

Bombesin stimulates distinct time-dependent changes in the <i>sn</i>-1,2-diradylglycerol molecular species profile from Swiss 3T3 fibroblasts as analysed by 3,5-dinitrobenzoyl derivatization and h.p.l.c. separation

Trevor R. Pettitt, Michael J.O. Wakelam · Biochemical Journal · 1993 · 58 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Activation of Phospholipase D and Phosphatidylinositol 4-Phosphate 5-Kinase in HL60 Membranes Is Mediated by Endogenous Arf but Not Rho

Ashley Martin, Fraser D. Brown, Matthew N. Hodgkin et al. · Journal of Biological Chemistry · 1996 · 46 citations · Full text

Life Sciences, Biophysics, Cell Signaling +12