A Phase II study of Bruceantin (NSC-165, 563) in advanced malignant melanoma

Bruceantin, a new potent antileukemic simaroubolide from Brucea antidysenterica

S. Morris Kupchan, Ronald W. Britton, Myra F. Ziegler et al. · The Journal of Organic Chemistry · 1973 · 268 citations

Pharmacy, Medicinal Chemistry, Pharmacology +5

Mode of Action of the Antitumor Compound Bruceantin, an Inhibitor of Protein Synthesis

S. Morris Kupchan, Susan Band Horwitz · Molecular Pharmacology · 1976 · 120 citations

Life Sciences, Biochemistry, Molecular Biology +13

Initial clinical studies with bruceantin.

Agop Y. Bedikian, Manuel Valdivieso, Gerald P. Bodey et al. · PubMed · 1980 · 21 citations

Medicine, Oncology, Pharmacology +16

Phase I trial of bruceantin.

Garnick Mb, Blum Rh, Canellos Gp et al. · PubMed · 1980 · 11 citations

Medicine, Oncology, Pharmacology +15