1‐Ethyl‐1,4‐dihydro‐4‐oxo‐7‐(pyridinyl)‐3‐quinolinecarboxylic acids. I. Synthesis of 3‐ and 4‐(3‐aminophenyl)pyridine intermediates

Philip M. Carabateas, R. Pauline Brundage, Karl O. Gelotte, M. D. GRUETT, Roman R. Lorenz, Chester J. Opalka, Baldev Singh, William H. Thielking, Gordon L. Williams, George Y. Lesher

Journal of Heterocyclic Chemistry · 1984 · 20 citations · 13 references

Concepts

Abstract

Abstract A series of substituted 3‐ and 4‐(3‐aminophenyl)pyridines has been prepared as intermediates for the synthesis of some 1‐alkyl‐1,4‐dihydro‐4‐oxo‐7‐pyridinyl‐3‐quinolinecarboxylic acids. The Hantzsch, Hauser and other pyridine syntheses were used. 4‐(3‐Aminophenyl)pyridine was prepared via 3‐(4‐pyridinyl)‐2‐cyclohexen‐1‐one using the Semmler‐Wolff reaction.

References

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