4-Substituted-2-phenylquinazolines as inhibitors of BCRP

The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

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Medicine, Oncology, Pharmacology +17

Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein.

Sridhar K. Rabindran, D D Ross, L. Austin Doyle et al. · PubMed · 2000 · 490 citations

Medicine, Oncology, Pharmacology +16

Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells.

Robert W. Robey, W Y Medina-Pérez, Kenryu Nishiyama et al. · PubMed · 2001 · 342 citations

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Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C.

Sridhar K. Rabindran, H He, Manu Smriti Singh et al. · PubMed · 1998 · 303 citations

Medicine, Oncology, Pharmacology +17

Gefitinib reverses breast cancer resistance protein–mediated drug resistance

Kae Yanase, Satomi Tsukahara, Sakiyo Asada et al. · Molecular Cancer Therapeutics · 2004 · 192 citations · Full text

Medicine, Oncology, Pharmacology +16