Spine · 2002 · 516 citations · 22 references
MedicineOrthopaedic SurgeryOrthopedic SurgeryPain ManagementPain MedicineSpine SurgeryAnalgesiaInjection TechniquesLumbar Spine SurgeryPain Management ProceduresPain OutcomesSpinal AnesthesiaLumbar Disc HerniationLumbosacral DiseasePatient Choice Of TreatmentPatient Satisfaction AnalysisRadicular Low Back PainRadicular PainRadiculopathy TreatmentTrigger Point Injection Therapy
STUDY DESIGN: A prospective study randomized by patient choice from the private practice of a single physician affiliated with a major teaching hospital was conducted. OBJECTIVES: To compare transforaminal epidural steroid injections with saline trigger-point injections used in the treatment of lumbosacral radiculopathy secondary to a herniated nucleus pulposus. SUMMARY OF BACKGROUND DATA: Epidural steroid injections have been used for more than half a century in the management of lumbosacral radicular pain. At this writing, however, there have been no controlled prospective trials of transforaminal epidural steroid injections in the treatment of lumbar radiculopathy secondary to a herniated nucleus pulposus. METHODS: Randomized by patient choice, patients received either a transforaminal epidural steroid injection or a saline trigger-point injection. Treatment outcome was measured using a patient satisfaction scale with choice options of 0 (poor), 1 (fair), 2 (good), 3 (very good), and 4 (excellent); a Roland-Morris low back pain questionnaire that showed improvement by an increase in score; a measurement of finger-to-floor distance with the patient in fully tolerated hip flexion; and a visual numeric pain scale ranging from 0 to 10. A successful outcome required a patient satisfaction score of 2 (good) or 3 (very good), improvement on the Roland-Morris score of 5 or more, and pain reduction greater than 50% at least 1 year after treatment. The final analysis included 48 patients with an average follow-up period of 16 months (range, 12-21 months). RESULTS: After an average follow-up period of 1.4 years, the group receiving transforaminal epidural steroid injections had a success rate of 84%, as compared with 48% for the group receiving trigger-point injections (P < 0.005). CONCLUSION: Fluoroscopically guided transforaminal injections serve as an important tool in the nonsurgical management of lumbosacral radiculopathy secondary to a herniated nucleus pulposus.
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A Study of the Natural History of Back Pain
Martín Roland, Richard Morris · Spine · 1983 · 3.4K citations
Corticosteroids and Lymphoid Cells
Henry N. Claman · New England Journal of Medicine · 1972 · 1K citations
Epidural Corticosteroid Injections for Sciatica Due to Herniated Nucleus Pulposus
Simon Carette, R Leclaire, Sylvie Marcoux et al. · New England Journal of Medicine · 1997 · 601 citations
Medicine, Anesthesiology, Surgery +14
High Levels of Inflammatory Phospholipase A2 Activity in Lumbar Disc Herniations
Joel S. Saal, Richard C. Franson, Robert J. Dobrow et al. · Spine · 1990 · 575 citations