A rapid method for the evaluation of compounds with mitochondria-protective properties

Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.

S T Smiley, Martin Reers, C Mottola-Hartshorn et al. · Proceedings of the National Academy of Sciences · 1991 · 1.6K citations · Full text

Proteinlipid Interaction, Intracellular Heterogeneity, Biochemistry +13

J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential

Martin Reers, Thomas W. Smith, L B Chen · Biochemistry · 1991 · 1K citations

A New Method for the Cytofluorometric Analysis of Mitochondrial Membrane Potential Using the J-Aggregate Forming Lipophilic Cation 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine Iodide (JC-1)

Andrea Cossarizza, M. Baccarani-Contri, Galina Kalashnikova et al. · Biochemical and Biophysical Research Communications · 1993 · 1K citations · Full text

Proteinlipid Interaction, Engineering, Biochemistry +14

JC‐1, but not DiOC₆(3) or rhodamine 123, is a reliable fluorescent probe to assess Δ<i>Ψ</i> changes in intact cells: implications for studies on mitochondrial functionality during apoptosis

Stefano Salvioli, Andrea Ardizzoni, Claudio Franceschi et al. · FEBS Letters · 1997 · 1K citations · Full text

Mitochondrial Membrane Potential and Nuclear Changes in Apoptosis Caused by Serum and Nerve Growth Factor Withdrawal: Time Course and Modification by (−)-Deprenyl

Jehangir S. Wadia, Ruth M.E. Chalmers-Redman, William Ju et al. · Journal of Neuroscience · 1998 · 229 citations · Full text

Apoptosis, Cell Death, Mitochondrial Biology +26