Journal of Clinical Investigation · 1945 · 335 citations · 5 references
MedicineCardiologyPhysiologyClinical CardiologyPulmonary Function TestingPulmonologyCardiac PhysiologyCardiovascular PhysiologyHemodynamicsArterial Carbon Dioxide ContentCarbon DioxideCardiac OutputFick Principle MeasurementMixed Venous Blood Gas CompositionPlasma Carbon Dioxide ContentVenous Carbon Dioxide Content
Determination of cardiac output on the basis of the so-called Fick principle requires the measurement of oxygen or of carbon dioxide content of arterial blood, and of mixed venous blood, and the total oxygen intake or carbon dioxide elimination by the lungs, per unit of time. With these values, cardiac output is obtained from either of the following two equations:
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Catheterization of the Right Auricle in Man
A. Cournand, Hilmert A. Ranges · Experimental Biology and Medicine · 1941 · 448 citations
Medicine, Cardiology, Physiology +7
Isaac Starr, John S. Donal, Alexander Margolies et al. · Journal of Clinical Investigation · 1934 · 52 citations · Full text
Clinical Tests of the Function of the Heart
JAMA · 1934 · 13 citations
Medicine, Cardiology, Physiology +12