Signal transduction pathway for l-ascorbic acid- and l-ascorbic acid 2-glucoside-induced DNA synthesis and cell proliferation in primary cultures of adult rat hepatocytes

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Harry Towbin, T. Staehelin, J. Gordon · Proceedings of the National Academy of Sciences · 1979 · 53.8K citations · Full text

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PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

Dario R. Alessi, Ana Cuenda, Philip Cohen et al. · Journal of Biological Chemistry · 1995 · 3.4K citations · Full text

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Chris J. Vlahos, William F. Matter, K. Y. Hui et al. · Journal of Biological Chemistry · 1994 · 3.2K citations · Full text

Specific Inhibitor, Molecular Pharmacology, Medicinal Chemistry +16

The mitogen-activated protein kinase signal transduction pathway

Roger J. Davis · Journal of Biological Chemistry · 1993 · 2.2K citations · Full text

Signal Transduction, Molecular Physiology, Signaling Pathway +7

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.

A. Ullrich, Andrew Gray, Albert W. Tam et al. · The EMBO Journal · 1986 · 1.9K citations · Full text

Molecular Physiology, Signal Transduction, Developmental Biology +13