S-Methylisothiourea sulfate improves renal, but not hepatic dysfunction in canine endotoxic shock model

Nitric oxide as a secretory product of mammalian cells

Carl Nathan · The FASEB Journal · 1992 · 4.4K citations

Life Sciences, Biochemistry, Cell Biology +10

Negative Inotropic Effects of Cytokines on the Heart Mediated by Nitric Oxide

Mitchell S. Finkel, Carmine V. Oddis, Timothy D. Jacob et al. · Science · 1992 · 1.6K citations

Veterinary Medicine, Pharmacology, Physiology +14

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

John D. MacMicking, Carl Nathan, Gary Hom et al. · Cell · 1995 · 1.4K citations · Full text

Life Sciences, Immunology, Microbiology +17

Protective and pathological roles of nitric oxide in endotoxin shock

Christine E. Wright, Daryl D. Rees, S. Moncada · Cardiovascular Research · 1992 · 595 citations

Veterinary Medicine, Pharmacology, Pharmacodynamics +12

Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo

Christoph Thiemermann, John R. Vane · European Journal of Pharmacology · 1990 · 528 citations

Life Sciences, Microbiology, Pharmacology +7