Chemical Communications · 2011 · 73 citations · 31 references
Enantioselective SynthesisEngineeringTerminal Aryl AlkynesOrganic ChemistryOrganometallic CatalysisCatalysisHomogeneous CatalysisChemistryAsymmetric CatalysisCatalytic Fecl3Head-to-head Dimerization
Iron can catalyze head-to-head dimerization of terminal aryl alkynes to give the corresponding (E) selective conjugated enynes in high yields. A variety of substituted aryl acetylenes underwent smooth dimerization using catalytic FeCl3 and DMEDA in the presence of KOtBu.
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The Atom Economy—A Search for Synthetic Efficiency
BM Trost · Science · 1991 · 4.7K citations
Combinatorial Chemistry, Inorganic Chemistry, Chemical Engineering +14