Clinical signs and symptoms associated with increased risk for thrombosis in patients with paroxysmal nocturnal hemoglobinuria from a Korean Registry

The Complement Inhibitor Eculizumab in Paroxysmal Nocturnal Hemoglobinuria

Peter Hillmen, Neal S. Young, Jörg Schubert et al. · New England Journal of Medicine · 2006 · 1.3K citations · Full text

Medicine, Hematology, Pharmacology +17

Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria

Junji Takeda, Toshio Miyata, Kazuyoshi Kawagoe et al. · Cell · 1993 · 1K citations

Life Sciences, Genetics, Hematology +9

Natural History of Paroxysmal Nocturnal Hemoglobinuria

Peter Hillmen, S. M. Lewis, Monica Bessler et al. · New England Journal of Medicine · 1995 · 901 citations · Full text

Medicine, Hematology, Molecular Medicine +14

Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria

Robert A. Brodsky, Neal S. Young, Elisabetta Antonioli et al. · Blood · 2007 · 653 citations

Medicine, Hematology, Pharmacology +11

Effect of Eculizumab on Hemolysis and Transfusion Requirements in Patients with Paroxysmal Nocturnal Hemoglobinuria

Peter Hillmen, Claire Hall, Judith Marsh et al. · New England Journal of Medicine · 2004 · 637 citations · Full text

Medicine, Hematology, Immunology +17