The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis

Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization

Elizabeta Nemeth, Marie S. Tuttle, Julie Powelson et al. · Science · 2004 · 4.8K citations

Medicine, Cell Biology, Physiology +17

A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis

John N. Feder, Andreas Gnirke, Zenta Tsuchihashi et al. · Nature Genetics · 1996 · 3.7K citations

Life Sciences, Genetics, Molecular Genetics +12

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

Hiromi Gunshin, Bryan Mackenzie, Urs V. Berger et al. · Nature · 1997 · 3.2K citations · Full text

Engineering, Biochemistry, Molecular Biology +10

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

François Tronche, Christoph Kellendonk, Oliver Kretz et al. · Nature Genetics · 1999 · 1.9K citations

Life Sciences, Neurobiology, Neuroscience +16

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

Adriana Donovan, Alison Brownlie, Yi Zhou et al. · Nature · 2000 · 1.7K citations

Medicine, Biology, Genetics +12