Concepedia

Alkylation as the Mechanism by which the Hepatotoxic Pyrrolizidine Alkaloids Act on Cell Nuclei

CCJ Culvenor, Arthur Thurlby Dann, A. T. Dick

Nature · 1962 · 95 citations · 17 references

DOI

Concepts

References

17

Structure and mechanism in organic chemistry

Harry S. Mosher · Journal of Chemical Education · 1954 · 313 citations

, , +11

Senecio Alkaloids: Primary Liver Tumours in Rats as a Result of Treatment with (1) A Mixture of Alkaloids from S. Jacobaea Lin.; (2) Retrorsine; (3) Isatidine

R. Schoental, M A Head, P. R. Peacock · British Journal of Cancer · 1954 · 143 citations

, , +8

The chronic pathological effects on the liver of the rat of the pyrrolizidine alkaloids heliotrine, lasiocarpine, and their <i>N</i>‐oxides

L. B. Bull, A. T. Dick · The Journal of Pathology and Bacteriology · 1959 · 80 citations

, , +12

Hepatotoxic Action of Pyrrolizidine (Senecio) Alkaloids in Relation to their Structure

R. Schoental · Nature · 1957 · 51 citations

, , +12

The mutagenic activity of some pyrrolizidine alkaloids inDrosophila

A.M. Clark · Molecular Genetics and Genomics · 1960 · 47 citations

, , +7