Concepedia

In Vitro Studies Investigating the Effect of Subcutaneous Phosphatidylcholine Injections in the 3T3-L1 Adipocyte Model: Lipolysis or Lipid Dissolution?

S. Klein, Stephan Schreml, Michael Nerlich, Lukas Prantl

Plastic & Reconstructive Surgery · 2009 · 51 citations · 17 references

DOI

Abstract

These results suggest that no enzymatic lipolytic pathway is induced. The decrease in volume after Lipostabil injections is likely attributable to the detergent effect of deoxycholate.

References

17

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Sebastian Schuck, Masanori Honsho, Kim Ekroos et al. · Proceedings of the National Academy of Sciences · 2003 · 653 citations · Full text

, , +13

Characterization of the solubilization of lipid bilayers by surfactants

Dov Lichtenberg · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1985 · 422 citations

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Phosphatidylcholine protects against fibrosis and cirrhosis in the baboon

C S Lieber, Sander J. Robins, Jianjun Li et al. · Gastroenterology · 1994 · 310 citations · Full text

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The increase in bilayer fluidity of rat liver plasma membranes achieved by the local anesthetic benzyl alcohol affects the activity of intrinsic membrane enzymes.

Larry M. Gordon, Richard Sauerheber, Judy A. Esgate et al. · Journal of Biological Chemistry · 1980 · 268 citations · Full text

, , +15

Detergent Effects of Sodium Deoxycholate Are a Major Feature of an Injectable Phosphatidylcholine Formulation Used for Localized Fat Dissolution

Adam M. Rotunda, Hiroyuki Suzuki, Ronald L. Moy et al. · Dermatologic Surgery · 2004 · 221 citations