Clinical Genetics · 1978 · 16 citations · 4 references
Life SciencesBiochemistryMolecular GeneticsBiochemical GeneticsEnzymologyNeuromuscular DisordersClinical EnzymologyMuscle DisordersMuscle PathologyMuscle PhysiologyMuscular DystrophyProtein ElectrophoresisAnalytical Detection LimitsCreatine Kinase-mbElectrophoresisMuscle Enzyme DisordersMuscle Enzyme TestingMuscular Dystrophy GeneticsMuscular Dystrophy PathophysiologySerum Creatine Kinase Assessment
Serum creatine kinase isoenzymes were studied in 41 patients suffering from Duchenne type muscular dystrophy and 20 mothers of patients (carriers) by cellulose acetate electrophoresis. Both the MM and MB types were found in all cases of Duchenne type dystrophy patients, and in carriers with highly elevated total creatine kinase activity BB was not observed above the detection limits of the methods used. However, a so-called atypical CK--BB band has been demonstrated.
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Atypical increase in serum creatine kinase activity in hospital patients.
Sylvan M Sax, John J. Moore, Joseph L. Giegel et al. · Clinical Chemistry · 1976 · 45 citations