ULTRASONICALLY ACCELERATED VILSMEIER HAACK CYCLISATION AND FORMYLATION REACTIONS

Abstract

ABSTRACT Ultrasonically irradiated Vilsmeier Haack (VH) reaction with acetanilides, hydrocarbons and acetophenones exhibited dramatic rate enhancements with excellent yields. The VH reaction with acetanilides afforded 2-chloro-3-formyl quinoline derivatives, hydrocarbons underwent formylation while hydroxy acetophenones yielded 3-formyl chromones.