Concepedia

Final report of a phase II evaluation of paclitaxel in patients with advanced squamous cell carcinoma of the head and neck

Arlene A. Forastiere, Darleen Shank, Donna Neuberg, Samuel G. Taylor, Ronald C. DeConti, George Adams

Cancer · 1998 · 200 citations · 6 references

DOI

Abstract

These results indicate that paclitaxel is an active agent for the treatment of squamous cell carcinoma of the head and neck. Studies evaluating alternative infusion schedules and combination regimens currently are underway.

References

6

Promotion of microtubule assembly in vitro by taxol

Peter B. Schiff, Jane Fant, Susan Band Horwitz · Nature · 1979 · 3.6K citations

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Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study.

Arlene A. Forastiere, Barbara Metch, Dorit Elisabeth Schuller et al. · Journal of Clinical Oncology · 1992 · 751 citations

A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck.

Charlotte Jacobs, Gary H. Lyman, E Vélez-García et al. · Journal of Clinical Oncology · 1992 · 631 citations

Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol.

Eric K. Rowinsky, Ross C. Donehower, RJ Jones et al. · PubMed · 1988 · 375 citations

, , +16

Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck

M. Clavel, Jan B. Vermorken, F. Cognetti et al. · Annals of Oncology · 1994 · 278 citations · Full text