Reactive Polymer Coatings that “Click”

Abstract

Everything just clicks into place: Alkyne-group functionalized polymer films that are deposited from the gas phase allow spatially defined immobilization of biomolecules, such as biotin, through the 1,3-dipolar cycloaddition click reaction with azide derivatives (see scheme). Such biofunctional surfaces have applications in diagnostics and biosensors. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z600357_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.