Concepedia

A phase 1, multicenter, open-label study of the safety of two dose levels of a human monoclonal antibody to human αv integrins, intetumumab, in combination with docetaxel and prednisone in patients with castrate-resistant metastatic prostate cancer

Franklin Chu, Joel Picus, Paula M. Fracasso, Robert Dreicer, Zhihui Lang, Brenda J. Foster

Investigational New Drugs · 2010 · 29 citations · 17 references

DOI

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References

17

Cancer Statistics, 2008

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2008 · 10.2K citations · Full text

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Docetaxel plus Prednisone or Mitoxantrone plus Prednisone for Advanced Prostate Cancer

Ian F. Tannock, Ronald de Wit, William R. Berry et al. · New England Journal of Medicine · 2004 · 5.7K citations

Requirement of Vascular Integrin α <sub>v</sub> β <sub>3</sub> for Angiogenesis

Peter C. Brooks, Richard A.F. Clark, David A. Cheresh · Science · 1994 · 3K citations

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

Peter C. Brooks, Anthony M.P. Montgomery, Mauricio Rosenfeld et al. · Cell · 1994 · 2.3K citations

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Control of Angiogenesis in Fibroblasts by p53 Regulation of Thrombospondin-1

Kristina M. Dameron, Olga V. Volpert, Michael A. Tainsky et al. · Science · 1994 · 1.4K citations

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