Concepedia

Crystal engineering of the composition of pharmaceutical phases

Rosa D. Bailey Walsh, M. W. Bradner, Scott G. Fleischman, Luis A. Morales, B. Moulton, Naír Rodríguez‐Hornedo, Michael J. Zaworotko

Chemical Communications · 2002 · 402 citations · 12 references

DOI

Concepts

Abstract

The carboxylic acid-pyridine supramolecular heterosynthon can be exploited to predictably generate binary crystalline phases involving rac-ibuprofen, rac-flurbiprofen or aspirin.

References

12

The Hydrogen Bond in the Solid State

Thomas Steiner · Angewandte Chemie International Edition · 2002 · 6.2K citations

, , +13

Supramolecular Synthons in Crystal Engineering—A New Organic Synthesis

Gautam R. Desiraju · Angewandte Chemie International Edition in English · 1995 · 4.8K citations

, , +16

Encoding and decoding hydrogen-bond patterns of organic compounds

Margaret C. Etter · Accounts of Chemical Research · 1990 · 4.6K citations

, , +8

Photodimerization in the solid state

G. Schmidt · Pure and Applied Chemistry · 1971 · 2.1K citations · Full text

, , +8

“Total Synthesis” Supramolecular Style: Design and Hydrogen-Bond-Directed Assembly of Ternary Supermolecules

Christer B. Aakeröy, A.M. Beatty, B.A. Helfrich · Angewandte Chemie International Edition · 2001 · 457 citations

, , +16