Clinical & Experimental Allergy · 1981 · 19 citations · 2 references
PharmacyPharmacologyPharmacotherapyDrug DeliveryPulmonary Drug DeliveryRespiratory PharmacotherapyAerosol TherapyAerosolized Medication DeliveryAsthma ManagementAsthma PharmacotherapyInhalation Dosage FormsInhalation Drug DeliveryHigh Humidity StressHumidityInhalation Powder Formulation
Summary Sodium cromoglycate (SCG) powder often clumps in the presence of high humidity, making inhalation ineffective. A pressurized aerosol containing 1 mg SCG per actuation was made; and a double‐blind cross‐over trial in twenty‐four young patients with perennial extrinsic asthma over 8 weeks showed that 2 mg of SCG aerosol was as effective as 20 mg of the powder, and almost all patients preferred using the aerosol.
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