Cerebral microbleeds are associated with worse cognitive function

Mariëlle M.F. Poels, M. Arfan Ikram, Aad van der Lugt, Albert Hofman, Wiro J. Niessen, Gabriël P. Krestin, Monique M.B. Breteler, Meike W. Vernooij

Neurology · 2012 · 375 citations · 28 references

Abstract

Presence of numerous microbleeds, especially in a strictly lobar location, is associated with worse performance on tests measuring cognitive function, even after adjustments for vascular risk factors and other imaging markers of small vessel disease. These results suggest an independent role for microbleed-associated vasculopathy in cognitive impairment.

References

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