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Elevated Serum Secretory IgA in Patients with IgA Nephropathy

DOI

11

Citations

0

References

1989

Year

Hideaki Yamabe, Kazuhiro Ozawa, K. Fukushi, Hiroharu Kubota, Hiroshi Ohsawa, Satoshi Seino, Hiroshi Inuma, Mariko Miyata, Takashi Sasaki, Kogo Onodera
˜The œNephron journals/Nephron journals

Abstract

Serum secretory IgA was measured to elucidate the significance of secretory IgA in patients with IgA nephropathy. The levels of serum secretory IgA and IgA were, respectively, 6.8 +/- 3.5 micrograms/ml and 231.0 +/- 69.2 mg/dl in the controls and 11.8 +/- 3.2 micrograms/ml and 385.3 +/- 78.7 mg/dl in the patients. The levels of serum secretory IgA and IgA in the patients were significantly higher than those in controls (p less than 0.01). Elevated serum secretory IgA may reflect the excessive state of the IgA-secreting system in IgA nephropathy patients.