Molecular characterization of the ldmdr1 multidrug resistance gene from Leishmania donovani

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.1K citations · Full text

Dna, Engineering, Dna Analysis +20

Improved tools for biological sequence comparison.

William R. Pearson, David J. Lipman · Proceedings of the National Academy of Sciences · 1988 · 11.3K citations · Full text

Genetics, Molecular Biology, Dna Sequences +18

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science · 1989 · 7.4K citations

Genetics, Molecular Biology, Pathology +17

CLUSTAL: a package for performing multiple sequence alignment on a microcomputer

Desmond G. Higgins, Paul M. Sharp · Gene · 1988 · 3.4K citations

Bioinformatics, Long-read Sequencing, Natural Sciences +11

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

Chang-jie Chen, Janice E. Chin, Kazumitsu Ueda et al. · Cell · 1986 · 1.9K citations

Antimicrobial Resistance Gene, Multidrug-resistant Human Cells, Health Sciences +11