Patterns of functional activity associated with cocaine self-administration in the rat change over time

THE [¹⁴C]DEOXYGLUCOSE METHOD FOR THE MEASUREMENT OF LOCAL CEREBRAL GLUCOSE UTILIZATION: THEORY, PROCEDURE, AND NORMAL VALUES IN THE CONSCIOUS AND ANESTHETIZED ALBINO RAT¹

Louis Sokoloff, Martin Reivich, Charles Kennedy et al. · Journal of Neurochemistry · 1977 · 6K citations

Life Sciences, Biochemistry, Neuroscience +12

Transition from Moderate to Excessive Drug Intake: Change in Hedonic Set Point

Serge H. Ahmed, George F. Koob · Science · 1998 · 1.2K citations

Nursing, Behavioral Sciences, Psychology +17

Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens.

Francesco E. Pontieri, Gianluigi Tanda, G. Di Chiara · Proceedings of the National Academy of Sciences · 1995 · 868 citations

Medicine, Neuroscience, Pharmacology +17

Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens

David C. S. Roberts, George F. Koob, P. Klonoff et al. · Pharmacology Biochemistry and Behavior · 1980 · 726 citations

Medicine, Neurobiology, Neuroscience +16

Postcocaine anhedonia. An animal model of cocaine withdrawal.

Athina Markou, G F Koob · PubMed · 1991 · 508 citations

Nursing, Neuroscience, Pharmacology +10