The Value of 18F-FLT PET for Detecting Second Primary Cancers and Distant Metastases in Head and Neck Cancer Patients

Abstract

FLT PET does not appear to be recommendable to replace FDG PET for pretreatment metastasis staging in HNSCC cases because of its lower sensitivity and higher background activity in the liver and bone marrow. However, it might provide additional diagnostic specificity and biological information.