Acral Melanoma Simulating Warts: Dermoscopic Clues to Prevent Missing a Melanoma

Abstract

In Brief Neisseria, of the family Neisseriacea, are gram-negative, nonmotile, and non–spore-forming bacteria. The pathogens Neisseria gonorrhoeae and Neisseria meningitidis have been extensively studied and have long been recognized as human-specific pathogenic bacteria. Other members of the Neisseria genus, are nonpathogenic and are normal inhabitants of the upper respiratory tract. However, recent reports suggest that these normally nonpathogenic bacteria have the potential to produce infection. Cases of Neisseria species causing bacteremia, endocarditis, and pneumonia have been documented, as well as infection in immune-compromised hosts. Currently, there is a paucity of data regarding Neisseria species infection in patients with cancer. We report a case series of nongonococcal and nonmeningococcal Neisseria infection in patients with underlying malignancy to add to this limited body of knowledge and to provide further evidence of the opportunistic potential of these species in immune-compromised hosts. Neisseria gonorrhea and Neisseria meningitidis have been extensively recognized as human-specific pathogenic bacteria. As the other members of the Neisseria genus, Neisseria spp., have been studied, it is now understood that the majority of human-associated Neisseria species are nonpathogenic. However, recent reports suggest their potential to produce infection. Cases of Neisseria spp. bacteremia, endocarditis, and pneumonia have been documented in immunecompromised hosts. The authors report a case series of Neisseria infection in patients with underlying malignancy.