Post-irradiation Brain Tumors

Abstract

Four cases of brain tumor—three meningiomas and one glioblastoma—that developed after radiation therapy are reported. The location and course of each tumor were highly suggestive of a pathogenetic role of the preceding irradiation in the development of the tumor. A review of the literature revealed that there is evidence for a causative role of irradiation in the development of brain tumors, although there has been no definitive epidemiological study.