Concepedia

The A431E mutation in PSEN1 causing Familial Alzheimer’s Disease originating in Jalisco State, Mexico: an additional fifteen families

Jill R. Murrell, Bernardino Ghetti, Elizabeth J. Cochran, Miguel Ángel Macías-Islas, Luis D. Medina, Arousiak Varpetian, Jeffrey L. Cummings, Mario F. Mendez, Claudia H. Kawas, Helena C. Chui,

Neurogenetics · 2006 · 76 citations · 4 references

Open access

Concepts

Life SciencesGeneticsMolecular GeneticsMedical GeneticsNeurodegenerationNeurogeneticsAlzheimer DiseaseGenetic DisordersNeurodegenerative Disease GeneticsNeurodegenerative DiseasesNeurodegenerative DisordersNeurogenetic DisordersAutosomal Dominant DementiaFamilial DementiaFamilial Neurodegenerative DiseaseMutationNeurodegeneration GeneticsNeurodegenerative GeneticsPsen1 Mutations

References

4

A Founder Mutation in Presenilin 1 Causing Early-Onset Alzheimer Disease in Unrelated Caribbean Hispanic Families

E Athan · JAMA · 2001 · 107 citations · Full text

Life Sciences, Genetics, Neurology +13

Founder effect for the Ala431Glu mutation of the presenilin 1 gene causing early-onset Alzheimer’s disease in Mexican families

Petra Yescas, Adriana Huertas‐Vázquez, Teresa Villarreal‐Molina et al. · Neurogenetics · 2006 · 61 citations

Life Sciences, Genetics, Molecular Genetics +17

Female preclinical presenilin-1 mutation carriers unaware of their genetic status have higher levels of depression than their non-mutation carrying kin

John M. Ringman · Journal of Neurology Neurosurgery & Psychiatry · 2004 · 37 citations · Full text

Life Sciences, Genetics, Psychiatry +17

Neuropsychological function in nondemented carriers of presenilin-1 mutations

John M. Ringman, Yolanda Marina Vargas-Rodríguez, Mireya Chávez et al. · Neurology · 2005 · 31 citations · Full text

Medicine, Genetics, Neurology +17