Concepedia

Tetrahydrobiopterin: a novel antihypertensive therapy

Marcus Porkert, Utkarsh A. Reddy, F Cheema, Christina Niessner, Paul Kolm, Dean P. Jones, Craig Hooper, W. Robert Taylor, David G. Harrison, Arshed A. Quyyumi

Journal of Human Hypertension · 2008 · 98 citations · 28 references

DOI

Concepts

References

28

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Robert F. Furchgott, John V. Zawadzki · Nature · 1980 · 12K citations

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Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

L J Ignarro, Georgette M. Buga, K S Wood et al. · Proceedings of the National Academy of Sciences · 1987 · 5.1K citations · Full text

, , +12

Role of endothelium-derived nitric oxide in the regulation of blood pressure.

Daryl D. Rees, Richard Palmer, Salvador Moncada · Proceedings of the National Academy of Sciences · 1989 · 1.8K citations · Full text

, , +12

Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors

Jeannette Vásquez‐Vivar, Balaraman Kalyanaraman, Pavel Martásek et al. · Proceedings of the National Academy of Sciences · 1998 · 1.5K citations

, , +11

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

Ulf Landmesser, Sergey Dikalov, S. Russ Price et al. · Journal of Clinical Investigation · 2003 · 1.5K citations · Full text

, , +16