The Rare Phenotype En(a‐) in a French‐Canadian Family

Abstract

A French-Canadian En(a-) propositus, whose red cells are phenotypically like the three previously reported, differs in the mode of reaction of this antibody which is apparently not immune. His consaguineous parents and 2 of this 4 sibs are heterozygous EnaEn, the other 2 being EnaEna. Sialic acid levels and the MN glycoprotein content of the red cells of the family and the PAS-straned patterns of the red cell membranes of the propositus confirm the serological findings.