Anti-Group B Streptococcus antibody in infants born to mothers with human immunodeficiency virus (HIV) infection

Abstract

Maternal HIV infection was associated with lower anti-GBS surface binding antibody concentration and antibody-mediated C3b/iC3b deposition onto GBS bacteria of serotypes Ia, Ib, II, III and V. This may render these infants more susceptible to early and late onset GBS disease.