Flavonoid effects on normal and leukemic cells

Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (necrosis)

Zbigniew Darżynkiewicz, Gloria Juan, Xun Li et al. · Cytometry · 1997 · 1.1K citations

Term Cell Necrobiology, Cell Necrobiology, Apoptosis +18

Flavopiridol Induces Apoptosis in Chronic Lymphocytic Leukemia Cells Via Activation of Caspase-3 Without Evidence of bcl-2 Modulation or Dependence on Functional p53

John C. Byrd, Charlotte Shinn, Jamie K. Waselenko et al. · Blood · 1998 · 280 citations

Protein kinase inhibitors flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia

Shinichi Kitada, Juan M. Zapata, Michael Andreeff et al. · Blood · 2000 · 249 citations

Differential regulation of primitive human hematopoietic cells in long- term cultures maintained on genetically engineered murine stromal cells

HJ Sutherland, CJ Eaves, PM Lansdorp et al. · Blood · 1991 · 245 citations · Full text

Flavopiridol induces apoptosis of normal lymphoid cells, causes immunosuppression, and has potent antitumor activity In vivo against human leukemia and lymphoma xenografts.

Francisco Arguello, Mark Alexander, Judith A. Sterry et al. · PubMed · 1998 · 242 citations