EFFECTS OF SYSTEMATIC 12-CORE BIOPSY ON THE PERFORMANCE OF PERCENT FREE PROSTATE SPECIFIC ANTIGEN FOR PROSTATE CANCER DETECTION

Abstract

The 12 core biopsy strategies have a higher cancer detection rate than sextant biopsies and they are gaining widespread acceptance. The addition of 6 laterally directed cores to traditional sextant biopsy may result in a modest decrease in the sensitivity of percent fPSA at each selected biopsy threshold without affecting specificity.