The tested simple algorithm proved to be useful in CK20 positive (+) cases, predicting a primary tumor localization in the colon, rectum, pancreas, or biliary tract with high accuracy. The CK20- group was too heterogeneous to be classified adequately by these two antibodies.
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Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies.
R. Moll, A D Lowe, Jürgen Laufer et al. · PubMed · 1992 · 813 citations · Full text