Journal of Cardiac Surgery · 2007 · 103 citations · 23 references
MedicineSurgeryResuscitationTrauma Critical CareVentilator ManagementAcute Respiratory DistressAcute Respiratory Distress SyndromeAcute Respiratory FailureExtracorporeal Life SupportExtracorporeal Membrane OxygenationMechanical VentilationBlunt Thoracic InjuryBlunt Thoracic TraumaBlunt Trauma CareBronchial InjuryExtubation In Trauma PatientsMechanical Ventilation In TraumaMediastinal EmphysemaRespiratory Support In Trauma
BACKGROUND: Despite recent advances in critical care management, the mortality of acute respiratory distress syndrome (ARDS) remains high. The final rescue therapy for patients with severe hypoxia refractory to conventional therapy modalities is the extracorporeal gas exchange. METHODS: We report the management of three polytraumatized patients with life-threatening injuries, severe blunt thoracic trauma, and consecutive ARDS treating by extracorporeal membrane oxygenation (ECMO). Two patients suffered a car accident with severe lung contusion and parenychmal bleeding. Bronchial rupture and mediastinal emphysema was found in one of them. Another patient developed ARDS after attempted suicide with multiple fractures together with blunt abdominal and thoracic trauma. RESULTS: All patients were placed on ECMO and could be rapidly stabilized. They were weaned from ECMO after a mean of 114 +/- 27 hours of support without complications, respectively. Mean duration of ICU stay was 37 +/- 23 days. CONCLUSIONS: Quick encouragement of ECMO for the temporary management of gas exchange may increase survival rates in trauma patients with ARDS.
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Alan H. Morris, C. Jane Wallace, R L Menlove et al. · American Journal of Respiratory and Critical Care Medicine · 1994 · 966 citations
UK collaborative randomised trial of neonatal extracorporeal membrane oxygenation
The Lancet · 1996 · 733 citations
Medicine, Pediatrics, Surgery +13