Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload

Topology of Superoxide Production from Different Sites in the Mitochondrial Electron Transport Chain

Julie St‐Pierre, Julie A. Buckingham, Stephen J. Roebuck et al. · Journal of Biological Chemistry · 2002 · 1.5K citations · Full text

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

Ethan J. Anderson, Mary E. Lustig, Kristen E. Boyle et al. · Journal of Clinical Investigation · 2009 · 1.2K citations · Full text

Mitochondrial α-Ketoglutarate Dehydrogenase Complex Generates Reactive Oxygen Species

Anatoly A. Starkov, Gary Fiskum, Christos Chinopoulos et al. · Journal of Neuroscience · 2004 · 680 citations · Full text

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

Casey L. Quinlan, Adam L. Orr, Irina V. Perevoshchikova et al. · Journal of Biological Chemistry · 2012 · 650 citations · Full text

Mitochondrial Function, Biochemistry, High Rates +11

S-glutathionylation uncouples eNOS and regulates its cellular and vascular function

Chun‐An Chen, Tse-Yao Wang, Saradhadevi Varadharaj et al. · Nature · 2010 · 575 citations

Inflammation, Molecular Physiology, Signal Transduction +11