High‐Throughput Screening of Catalysts by Combining Reaction and Analysis

Oliver Trapp, Sven K. Weber, Sabrina Bauch, Werner Hofstadt

Angewandte Chemie International Edition · 2007 · 116 citations · 19 references

Concepts

Abstract

Drudgery minimized, efficiency maximized: By combining catalysis and separation in microcapillaries greater than 2 cm in length, it is possible to efficiently determine the reaction kinetics for entire libraries of substrates. This was demonstrated for hydrogenations over highly active Pd nanoparticles and ring-closing metatheses over the Grubbs 2nd generation catalyst. R: reagents, P: products.

References

19