Journal of Pediatric Orthopaedics · 2005 · 52 citations · 10 references
MedicineOrthopaedic SurgeryOrthopedic SurgeryOrthopedicsSpinal BiomechanicsSpine SurgeryCerebral PalsyPediatric ScoliosisPediatric Spine SurgerySpasticity ManagementSpasticity SurgerySpinal DeformityCerebral Palsy OrthopaedicsCerebral Palsy OrthopedicsCerebral Palsy-associated ScoliosisPostoperative Complications In ScoliosisPostoperative RadiographsRadiographic Evaluation Of ScoliosisRevisions
Placement of an intrathecal baclofen pump is a common treatment of spasticity in cerebral palsy patients. Though effective, the hardware is prone to malfunction, and multiple revisions are often necessary. Additional complications have also been described, including infection and drug toxicity or withdrawal. The authors report another complication of intrathecal baclofen therapy: accelerated progression of scoliosis after pump insertion. A retrospective chart review was performed on four patients who showed accelerated scoliotic progression after intrathecal baclofen pump insertion for treatment of spasticity. Cobb angles were measured from preoperative and postoperative radiographs to determine the rate of scoliotic degeneration both before and after pump insertion. Although there may not be a direct correlation between intrathecal baclofen and scoliosis, the authors consider the issue important enough to warrant discussion with any patient considering intrathecal baclofen.
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Intrathecal Baclofen for Severe Spinal Spasticity
Richard D. Penn, Suzanne M. Savoy, Daniel M. Corcos et al. · New England Journal of Medicine · 1989 · 750 citations
Medicine, Neurology, Neurosurgery +17
Intrathecal Baclofen for Spasticity in Cerebral Palsy
A. Leland Albright · JAMA · 1991 · 284 citations
Pharmacy, Neurology, Pharmacotherapy +14
Natural history of scoliosis in spastic cerebral palsy
Naoto Saito, Sohei Ebara, Kuniyoshi Ohotsuka et al. · The Lancet · 1998 · 275 citations