On-off phenomenon in a child with tetrahydrobiopterin deficiency due to 6-pyruvoyl tetrahydropterin synthase deficiency (BH4 deficiency)

Biochemical pathophysiology of Parkinson's disease.

O Hornykiewicz, Stephen J. Kish · PubMed · 1987 · 852 citations

Life Sciences, Neurology, Neuroscience +12

Analysis of cysteinyldopas, dopa, dopamine, noradrenaline and adrenaline in serum and urine using high-performance liquid chromatography and electrochemical detection

Christer Hansson, G Agrup, H Rorsman et al. · Journal of Chromatography B Biomedical Sciences and Applications · 1979 · 131 citations

Life Sciences, Biochemistry, Pharmacology +10

Plasma dopa concentrations and the “on‐off” effect after chronic treatment of Parkinson's disease

Richard D. Sweet, Fletcher McDowell · Neurology · 1974 · 72 citations

Medicine, Neurology, Pharmacology +17

Fluctuation in response to chronic levodopa therapy: pathogenetic and therapeutic considerations.

T. N. Chase, Jorge L. Juncos, Carlo Serrati et al. · PubMed · 1987 · 24 citations

Medicine, Pharmacology, Pharmacotherapy +12

Pharmacokinetics of levodopa and motor fluctuations.

R Hardie, Lees Aj, Stern Gm · PubMed · 1987 · 15 citations

Medicine, Pharmacokinetics, Pharmacology +11