Clinical relevance and cost‐effectiveness of <scp>HLA</scp> genotyping in children with Type 1 diabetes mellitus in screening for coeliac disease in the Netherlands

Abstract

The risk of coeliac disease development in children with Type 1 diabetes mellitus is increased when they are heterozygote DQ2.5/DQ8, homozygote or heterozygote DQ2.5. The implementation of HLA genotyping as a first-line screening tool has to be reconsidered because it is not distinctive or cost-effective.